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标题: Assiociate Professor
学院: Public Health and Health Professions; Medicine
Department: Department of Epidemiology
研究 Interests: Ecology of gut microbiota
Curriculum vitae:PDF格式

Dr. Mai and his lab investigate the complexity and dynamics of naturally occurring microbial communities inhabiting the digestive tracks of humans. Individuals typically have their own unique composition of intestinal microbiota, but Mai’s studies seek to determine predictable patterns of species complexity and dynamics that can evaluate an individual’s susceptibility to disease. He and his lab analyze gut microbiota for associations between its composition, the host’s diet, and the host’s state of health or disease. Dr. Mai’s lab also examines whether or not an individual’s intestinal microbiota composition affects their susceptibility to intestinal pathogens (particularly those causing diarrheal diseases), and if manipulation of this microbiota can help to prevent disease frequency or severity.

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By establishing known patterns of association between an individual’s intestinal microbiota and various diseases, Dr. Mai intends for his lab to eventually design specific probiotic interventions, aimed at improving microbiota composition, to increase an individual’s resistance to acute or chronic infections that can result in the development of more chronic disease. Dr. Mai’s training in epidemiology facilitates the expansion of his microbiota research from the laboratory to animal experiments and large population based studies. His work is unique in that it crosses several scales of study: he collects samples from human populations, performs analyses and experiments at the molecular level (often using experimental animal models), to then apply the findings back to large human population studies.>

The American Cancer Association is supporting Dr. Mai’s ongoing clinical study that investigates how differences in diet between African Americans and Caucasians can result in different microbiota compositions, and how these differences might contribute to the increased risk of colorectal cancer in African Americans.

Contact information:
Emerging 病原体 Institute
University of Florida
P.O. Box 100009
Gainesville, Florida 32610-00090
Voice: (352) 273-9398
Fax: (352) 273-9399
电子邮件: VMai@ufl.edu